Travel Bingo comes with ten dice featuring objects that might be seen while driving, such as animals, vehicles, and buildings. Players roll the dice into the included tray, and then try to spot the objects for points. Before rolling, one die is set aside to customize the game to the players' location. (For example, the orange die has farm-related objects, so it is set aside if the players are in a town or city.)

The game is designed for a single player or multiple players working cooperatively, but includes rules for playing competitively with multiple sets.